The Comprehensive Science of Wrinkle Treatment: Mechanisms, Modalities, and Modern Approaches

Wrinkle Treatment

I. Fundamental Physiology of Skin Aging 1.1 Structural Hierarchy of Facial Skin The integumentary system’s aging process manifests through three anatomical layers: Epidermis: Stratum corneum thinning (0.5μm/year post-30), reduced keratinocyte turnover (40-60 day cycle vs. youth 28 days) Dermis: Annual 1% collagen loss (Type I/III), elastin fragmentation, GAG depletion (50% HA reduction by age 50) […]

The Comprehensive Science and Clinical Practice of Mesotherapy

Mesotherapy

I. Introduction to Mesotherapy Mesotherapy represents a paradigm shift in minimally invasive aesthetic medicine, merging pharmacological precision with anatomical targeting. At M Medi Spa in Markham, Ontario, our licensed practitioners employ mesotherapy as a foundational therapy to address dermatological and metabolic concerns through customized intradermal and subcutaneous delivery of bioactive compounds. Unlike systemic medications, mesotherapy achieves localized therapeutic effects by administering microdoses […]